Faye33 wrote: I've been on Tamoxifen for about a year and a half now, and I swear that in the last three months or so, my neuropathy has worsened. I experienced pretty severe neuropathy while on Taxol, so much so that they lowered my dose for a couple treatments and totally canceled my last dose. I've been done with Taxol for almost a year and a half now. My neuropathy eventually diminished to the point where only the ends of a couple of fingers on each hand felt slightly numb, which my oncologist won't admit is residual neuropathy. Now, my feet hurt when I wake up in the morning, similar to what I remember them feeling like while on Taxol, just not as intense or painful. Now all of my fingers have a numb sensation on the tip of them, and now (within the past couple of days) part of my left foot feels numb. I get arm "bone freeze" pain when I work with cold foods, much like while I was on taxol. Neuropathy is the general term for pain or discomfort caused by damage to the nerves of the peripheral nervous system. Your peripheral nervous system is made up of the many nerves that bring signals from the brain and spinal cord to other — or peripheral — parts of the body, such as the hands and feet. Damage to those nerves can affect the way the body sends signals to muscles, joints, skin, and internal organs. This can cause pain, numbness, loss of sensation, and other symptoms. For people with breast cancer, the most common cause of uncomfortable or even painful neuropathy that limits activity is chemotherapy — often referred to as chemotherapy-associated peripheral neuropathy. Chemotherapy medications travel throughout the body, where they can cause damage to the nerves. Chemotherapy medications that can cause neuropathy include: Chemotherapy-associated neuropathy can start any time after treatment begins, and it may worsen as treatment continues. Xanax for ibs Where can i buy real cialis online Azithromycin 200mg Can tamoxifen cause neuropathy - Forget about the embarrassment purchasing treatments in local drugstores – get the benefit of online shopping purchase. Kariena wrote Hi Ladies. I have been on Tamoxifen for 4 years now and my feet are uncomfortable most of the time tingling sensation - it. Tamoxifen TAM is an important cancer therapeutic and an. of a large fibre neuropathy, which is known to accompany non-hormonal. Tamoxifen is a hormonal therapy used to reduce the risk of cancer returning. It is a SERM, or selective estrogen receptor modulator, a medicine that prevents estrogen signals from getting to breast cancer cells. This medicine may also be called Nolvadex or Soltamox, in a liquid form. Tamoxifen is standard treatment for premenopausal and perimenopausal women with hormone receptor-positive breast cancer. In postmenopausal women, tamoxifen may be used alone or before an aromatase inhibitor. In early-stage breast cancer, no matter what your menopausal status, tamoxifen used after other treatment reduces the risk of cancer coming back. The benefit happens during the therapy and continues afterward for many years. Studies show breast cancer deaths to be down 30 percent in women 15 years beyond the start of tamoxifen treatment. Commonly reported side effects of tamoxifen include: amenorrhea, fluid retention, hot flash, nausea, vaginal discharge, vaginal hemorrhage, weight loss, and skin changes. Other side effects include: infection, sepsis, alopecia, constipation, cough, diarrhea, edema, increased serum aspartate aminotransferase, infrequent uterine bleeding, menstrual disease, ostealgia, vomiting, and weight gain. See below for a comprehensive list of adverse effects. Applies to tamoxifen: oral solution, oral tablet Along with its needed effects, tamoxifen may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking tamoxifen: Some side effects of tamoxifen may occur that usually do not need medical attention. "UK Summary of Product Characteristics." O 0Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. These side effects may go away during treatment as your body adjusts to the medicine. Tamoxifen neuropathy Differential effects of tamoxifen and anastrozole on optic cup size in., Breast Cancer Topic Tamoxifen and peripheral neuropathy? Were to buy aciclovirSertraline en espanolCytotec for cervical ripeningBuy flagyl gel onlineCheap cialis generic online Tamoxifen and Bortezomib to Treat Recurrent Brain Tumors The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U. S. Federal Government. Tamoxifen and Bortezomib to Treat Recurrent Brain Tumors - Full Text.. Tamoxifen induces cellular stress in the nervous system by inhibiting.. PDF Tamoxifen associated bilateral optic neuropathy. Neuropathy - peripheral is found among people who take Tamoxifen citrate, especially for people who are female, 60+ old also take medication Megace, and have Migraine. This study is created by eHealthMe based on reports of 9,041 people who have side effects when taking Tamoxifen citrate from FDA, and is updated regularly. Arimidex neuropathy. Hi Thomas - I had FEC chemo in 2003, 25 rads, 2 months of tamoxifen, then 4 yrs on Arimidex. I have been having severe hip, foot and hand. I am worried about long term effects as I am developing neuropathy in my feet and am. The mechanism of action of tamoxifen is to block estrogen, not decrease.