Antabuse drug

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  1. AndreyUa Well-Known Member

    Antabuse drug


    Normalerweise wird in der Leber der aufgenommene Alkohol über die Zwischenstufe Acetaldehyd zur Essigsäure umgewandelt, ähnlich wie bei der Essigherstellung durch Gärung. In diesen Abbau des Alkohols greift nun das Medikament ein und verhindert den letzten Schritt zur Umwandlung in die Essigsäure durch Blockade des Enzyms Aldehyddehydrogenase. Die Folge ist, dass sich der Acetaldehyd anreichert. Dieses bewirkt das sogenannte Acetaldehydsyndrom, welches darin besteht, dass, sobald Alkohol auch in geringen Dosen eingenommen wird, starke und unangenehme Unverträglichkeitsreaktionen entstehen, wie Hautrötung, Kältegefühl in den Armen und Beinen, Übelkeit, Kopfschmerzen und vor allem Herzrasen und Blutdruckabfall bis hin zum Herz-Kreislauf-Schock. Hierdurch kann bei gefährdeten Personen sogar Herzenge, Angina pectoris, und ein Herzinfarkt ausgelöst werden. Entsprechende Arzneimittel werden als Tabletten verabreicht. Es kann auch als Depotpräparat unter die Haut implantiert werden. Da die angesprochenen Unverträglichkeitsreaktionen bei Einnahme größerer Alkoholmengen sogar tödlich sein können (Acetaldehyd ist giftig), werden disulfiramhaltige Präparate nur noch selten und bei solchen Patienten angewandt, bei denen von guter Mitarbeit bei der Behandlung ausgegangen werden kann. Diverse Antibiotika, einige Antidiabetika und weitere Medikamente sowie das Pilzgift Coprin haben in Kombination mit Alkohol die gleiche Wirkung wie Disulfiram (siehe Acetaldehydsyndrom). A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome).

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    There are good prescription drugs, bad ones, and then there is Antabuse generic name disulfiram. It is both. Antabuse works, but you'd better. Learn about Antabuse Disulfiram may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Disulfiram, USP is an alcohol antagonist drug. CHEMICAL NAME - bisdiethylthiocarbamoyl disulfide. STRUCTURAL FORMULA - C10H20N2S4 M. W. 296.54.

    Antabuse (disulfiram) blocks an enzyme that is involved in metabolizing alcohol intake. Disulfiram produces very unpleasant side effects when combined with alcohol in the body. Antabuse is used in certain people with chronic alcoholism. This medicine can help keep you from drinking because of the unpleasant side effects that will occur if you consume alcohol while taking Antabuse. Antabuse is used together with behavior modification, psychotherapy, and counseling support to help you stop drinking. You should not use Antabuse if you have recently taken metronidazole or paraldehyde, or if you have consumed any foods or products that contain alcohol (mouthwash, cough medicine, cooking wine or vinegar, certain desserts, and others). Antabuse should never be given to a person without his or her knowledge of taking the medicine. Do not take Antabuse if you have consumed alcohol within the past 12 hours. Medication alone own cannot overcome an alcohol addiction. But medication in combination with other treatment such as counselling, self-help groups, developing recovery skills and relapse prevention techniques has be proven to increase the chances of overcoming alcoholism. There are three anti-alcohol drugs available: I will begin with Antabuse, since it is the most well studied. Important: This is general medical information, and is not tailored to the needs of a specific individual. It does not cover all possible precautions, side effects, or interactions. You should always consult your physician when making decisions about your health. And you should consult your physician before starting or stopping medication. I have no financial interest in any of these medications.

    Antabuse drug

    Disulfiram - DrugBank, Antabuse Disulfiram Side Effects, Interactions, Warning, Dosage.

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  5. Disulfiram INN, auch Tetraethylthiuramdisulfid TETD, Handelsname Antabus ® ist ein. Antabuse disulfiram as a pilot case of nonprofit drug. International.

    • Disulfiram – Wikipedia.
    • DailyMed - ANTABUSE- disulfiram tablet.
    • Antabuse Disulfiram - Side Effects, Dosage, Interactions - Drugs.

    In fact, many newly sober alcoholics take Antabuse also known as Disulfiram, a drug that was discovered in the 1920s when researchers. It is not known if disulfiram crosses the placenta, but the molecular weight of the drug suggests that placental transfer is likely. Various abnormalities e.g. club. Aug 15, 2017. Never give disulfiram to a patient in a state of alcohol intoxication or without the patient's full knowledge. The patient should not take disulfiram.

     
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    Antabuse Treatment for Alcoholism - Verywell Mind Jun 16, 2018. Antabuse, or disulfiram as it is also known, was the first medicine. abuse and alcohol dependence by the U. S. Food and Drug Administration.

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    Antabuse Treatment for Alcoholism - Verywell Mind Jun 16, 2018. Antabuse, or disulfiram as it is also known, was the first medicine. abuse and alcohol dependence by the U. S. Food and Drug Administration.

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