There is a “black box” warning associated with Metformin. The concern is “Lactic Acidosis” which is a complication that can occur from taking Metformin, which increases due to renal or hepatic impairment, acute congestive heart failure, sepsis, dehydration or excess alcohol intake. Metformin is an oral antidiabetic drug whose classification is that of a biguanide. It is often the drug of choice for the treatment of type 2 diabetes, particularly among patients who are overweight and who’ve got normal kidney functionality. Metformin is also used in the treatment of polycystic ovary syndrome and has been researched into for other diseases where insulin resistance is often a critical factor. Metformin actively works by suppressing glucose production in the liver. Metformin has been shown to be the only antidiabetic drug that’s conclusively shown to prevent cardiovascular complications from diabetes. Diabetes is a disease that affects how the body regulates blood sugar. It can cause severe complications if left unchecked, such as heart disease, kidney damage, and worse. That’s why so many people were excited when Merck & Co. announced that a breakthrough drug called sitagliptin could help regulate blood glucose with fewer side effects than existing type 2 diabetes medications. Merck combined this new drug sitagliptin with metformin to create Janumet. It was quickly revealed that drugs containing sitagliptin did carry several side effects, including lactic acidosis, pancreatitis, and even cancer. Janumet is a combination of two previously approved type 2 diabetes drugs — sitagliptin and metformin. As a result, hundreds filed lawsuits against Merck and other makers of similar type 2 diabetes medications. Metformin is one of the first medications given to those with type 2 diabetes. Viagra shoppers drug mart Where can i purchase zovirax ointment Nolvadex results However, side effects include bladder cancer and heart failure. daily alone or with other antidiabetic medications such as Glucophage metformin. arisen over serious adverse events such as kidney disease, bladder cancer, and bone. Thousands of Actos lawsuits have been filed against both Takeda and Eli Lilly who. If you believe you have an injury or illness as a result of a Type 2 diabetes drugs. as a combination drug – it combines sitagliptin and metformin into a single pill. linked to kidney problems such as diabetic ketoacidosis and kidney failure. It can cause severe complications if left unchecked, such as heart disease, kidney damage, and worse. That's why so many people were excited when Merck. « Invokana / Farxiga / Jardiance: Urinary Tract Infections Leading To Urosepsis And Pyelonephritis Are Lesser Known Side Effects | Main | Denosumab Drugs Prolia And Xgeva Linked To QT Interval Prolongation Associated With Hypocalcemia » (Posted by Tom Lamb at Drug Injury Watch.com) This article will feature three types of drug injury cases that are starting to gain some momentum in terms of the number of lawsuits filed against the responsible pharmaceutical companies in courts across the country. (1) Diabetes Medicines in the Sodium-Glucose Co-Transporter-2 (SGLT2) Inhibitors Class of Drugs Invokana (canagliflozin) — Janssen Pharmaceuticals Invokamet (canagliflozin and metformin) — Janssen Pharmaceuticals Farxiga (dapagliflozin) — Astra Zeneca Pharmaceuticals Xigduo XR (dapagliflozin and metformin extended-release) — Astra Zeneca Pharmaceuticals Jardiance (empagliflozin) — Boehringer Ingelheim Pharmaceuticals Glyxambi (empagliflozin and linagliptin) — Boehringer Ingelheim Pharmaceuticals Synjardy (empagliflozin and metformin hydrochloride) — Boehringer Ingelheim Pharmaceuticals and Eli Lilly and Company Adcirca (tadalafil) -- Eli Lilly and Company Cialis (tadalafil) -- Eli Lilly and Company Levitra (vardenafil hydrochloride) -- Glaxo Smith Kline Revatio (sildenafil citrate) -- Pfizer Staxyn (vardenafil hydrochloride) -- Glaxo Smith Kline Stendra (avanafil) -- Vivus and Auxilium Pharmaceuticals Viagra (sildenafil citrate) -- Pfizer These various prescription drug products have been linked to malignant melanoma skin cancer (but not basal or squamous cell skin cancers). (3) Heartburn Medicines and Acid Reflux Pills like Prevacid, Prilosec, and Nexium in the Proton Pump Inhibitors (PPIs) Class of Drugs Nexium (esomeprazole magnesium) [prescription drug] == Astra Zeneca LPNexium 24HR (esomeprazole magnesium) [over-the-counter] -- Pfizer Consumer Healthcare Prilosec (omeprazole) [prescription drug] -- Astra Zeneca LPPrilosec OTC (omeprazole) [over-the-counter] -- Procter & Gamble Manufacturing Co. Prevacid (lansoprazole) [prescription drug] -- Takeda Pharmaceuticals America, Inc. Prevacid 24 HR (lansoprazole) [over-the-counter] -- Novartis Consumer Health, Inc. We are currently investigating possible drug injury lawsuits against the responsible pharmaceutical companies for patients using these drugs who have developed the side effects listed above. For more information, see these web pages at our Drug Injury Law: Medical & Legal Information site: Invokana / Farxiga / Jardiance / Invokamet / Xigduo / Glyxambi / Synjardy Viagra / Cialis / Levitra / Staxyn / Stendra / Revatio / Adcirca Nexium / Prilosec / Prevacid We have been representing patients and their family in drug injury lawsuits for the past 16 years and this is our main practice area. Drug Injury Law.com: Medical & Legal Information About Drug Side Effects (All website content by attorney Tom Lamb) Drug Injury Case Evaluation - Free. A number of diabetes drugs have been linked in studies and lawsuits to serious drug side effects, including acute pancreatitis and pancreatic cancer. Some class action diabetes lawsuits have resulted in settlements with the plaintiffs. Whereas type 1 diabetics need to inject insulin several times a day to stay alive, type 2 diabetics are treated with a variety of glucose-lowering drugs, and combinations thereof. Type 2 diabetes occurs when the pancreas doesn't produce enough insulin to maintain a normal blood glucose level, or the body is unable to use the insulin that is produced. Diabetes, a lifelong condition, causes a person's blood sugar level to become too high. Four main risk factors for developing type 2 diabetes are genetics, age, weight and ethnicity. Almost 26 million Americans have diabetes, and up to 95 percent of these cases are type 2 diabetes. There are several classes of diabetes drugs that work in different ways to lower blood sugar (glucose). Metformin kidney damage lawsuit Can I sue advil and metformin for kidney failure -, Diabetes Drug Lawsuit - TorHoerman Law Viagra plus dapoxetineDoxycycline when to take Invokana Lawsuit Investigation of Kidney Failure, Ketoacidosis and Other. Invokana canagliflozin; Invokamet canagliflozin/metformin. Invokana Kidney Failure Lawsuit Kitrick, Lewis & Harris Co. L. P. A.. Sitagliptin & Metformin Lawsuit Janumet Side Effects. Metformin in People With Kidney Disease - Diabetes Self.. Actually, metformin is usually not the original cause of kidney problems. chemistry balance of your blood and can lead to kidney failure and other organ failure. Metformin Side Effects. Metformin may cause other side effects. stomach pain ; gas; constipation; unpleasant metallic taste in mouth. Metformin has been known to cause kidney and liver problems, but this does not happen in all patients, and there is some evidence there is a co-factor, in development of damage, such as alcoholism, or a combination of other drugs.