Neurontin is a modern highly effective drug for the peroral monotherapy of the neuropathic pain. This drug provides the anticonvulsive and antiepileptic action. It carries out the function of the breaking mediator in the central nervous system. It easily penetrates into the tissue of the brain and prevents spasms caused by the maximal electric shock, chemical drugs includi ng inhibitors of synthesis of GABA, and also conditioned by the genetic factors. After the consumption of the drug the maximal concentration in the body is observed in 2-3 hours. The consumption of meals does not provide a weakening of the efficiency, and therefore the tablets of Neurontin may be taken both before and after meals. The active components are excreted by kidneys from the body in the invariable type in 7-8 hours after the use. Neurontin helps to get rid of the different partial spasms and also neuropathic pain. Neurontin capsules 100mg are used to treat epilepsy to control seizures in several forms of epilepsy, ranging from partial to generalized tonic-clonic seizures, in adults who have not responded to other antiepileptic drugs; also to control partial seizures in children. Neurontin capsules are also used to control neuropathic (nerve) pain in adults, including, painful diabetic neuropathy and post-herpetic neuralgia, caused by shingles (herpes zoster), to reduce pain sensations primarily in the arms and legs, such as burning stabbing shooting or shooting pain, with tingling numbness or pins and needles. Neurontin capsules 100mg contain gabapentin, an anticonvulsant that is thought to work by controlling certain neurotransmitters (chemicals that allow nerve cells to communicate) that send nerve signals from the brain causing seizures or nerve pain. Gabapentin in Neurontin capsules is an analogue of, and has a similar chemical structure to the neurotransmitter GABA (gamma-aminobutyric acid). GABA is the major inhibitory neurotransmitter that reduces transmission of nerve signals from the brain to other parts of the central nervous system. Gabapentin in Neurontin capsules does not work through the same receptors as GABA and therefore has a different mechanism of action to other GABA analogues like barbiturates and benzodiazepines, however, it does bind to a receptor in the brain, that has yet to be determined and it is thought to control neurotransmission via voltage-gated calcium channels, which are ion channels in the cell membranes of nerve cells involved in the propagation of electrical signals. Neurontin capsules 100mg reduce the amount of nerve excitation that causes epileptic seizures and nerve pain, which helps control symptoms associated with epilepsy and neuropathic pain. 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