Azithromycin for infants

Discussion in 'Canadapharmacy' started by worka, 26-Aug-2019.

  1. ShurupS New Member

    Azithromycin for infants


    Each 5 ml prepared suspension contains 204.8 mg azithromycin monohydrate equivalent to 200 mg azithromycin. Each 1 ml prepared suspension contains 40.96 mg azithromycin monohydrate equivalent to 40 mg azithromycin. Excipients with known effect: • Sucrose 3.70 g/ 5 ml • Aspartame (E951) 0.030 g/ 5 ml • Sodium 7.739 mg (0.336 mmol) /5 ml For the full list of excipients, see section 6.1. Azithromycin powder for oral suspension is indicated for the treatment of the following infections, when caused by micro-organisms sensitive to azithromycin (see section 4.4 and 5.1): - acute bacterial sinusitis (adequately diagnosed) - acute bacterial otitis media (adequately diagnosed) - pharyngitis, tonsillitis - acute exacerbation of chronic bronchitis (adequately diagnosed) - mild to moderately severe community acquired pneumonia - skin and soft tissue infections - uncomplicated Chlamydia trachomatis urethritis and cervicitis Considerations should be given to official guidance on the appropriate use of antibacterial agents. Adults In uncomplicated Chlamydia trachomatis urethritis and cervicitis, the dose is 1,000 mg in one single oral dose. For all other indications the dose is 1,500 mg, to be administered as 500 mg per day for three consecutive days. Alternatively the same total dose (1,500 mg) can also be given over a period of 5 days with 500 mg on the first day and then 250 mg on days 2 to 5. Azithromycin tablets can be applied for the treatment of the following infections, when caused by microorganisms sensitive to azithromycin (see sections 4.4 and 5.1): - acute bacterial sinusitis (adequately diagnosed) - acute bacterial otitis media (adequately diagnosed) - pharyngitis, tonsillitis - acute exacerbation of chronic bronchitis (adequately diagnosed) - mild to moderately severe community acquired pneumonia - skin and soft tissue infections - uncomplicated Chlamydia trachomatis urethritis and cervicitis Considerations should be given to official guidance on the appropriate use of antibacterial agents. Adults In uncomplicated Chlamydia trachomatis urethritis and cervicitis the dose is 1000 mg as a single oral dose. For all other indications the dose is 1500 mg, to be administered as 500 mg per day for three consecutive days. As an alternative the same total dose (1500 mg) can also be administered over a period of five days with 500 mg on the first day and 250 mg on the second to the fifth day. Elderly people The same dose as in adult patients is used for elderly people. Since older people can be patients with ongoing proarrhythmic conditions a particular caution is recommended due to the risk of developing cardiac arrhythmia and torsades de pointes (see section 4.4). Paediatric population Azithromycin tablets should only be administered to children weighing more than 45 kg when normal adult dose should be used.

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    Sutton AL, Acosta EP, Larson KB, Kerstner-Wood CD, Tita AT, Biggio JR. Perinatal pharmacokinetics of azithromycin for cesarean prophylaxis. Am J Obstet Gynecol. 2015. Azithromycin is an antibiotic useful for the treatment of a number of bacterial infections. This includes middle ear infections, strep throat, pneumonia, traveler's. Establishes the medication azithromycin Zithromax, Zithromax Tri-Pak, Zithromax Z-Pak, Zmax, a drug that is effective against susceptible bacteria causing.

    Community-acquired pneumonia: Oral: -Immediate-release: 500 mg orally as a single dose on day 1, followed by 250 mg orally once a day on days 2 to 5 -Extended-release: 2 g orally once as a single dose Parenteral: 500 mg IV once a day as a single dose for at least 2 days, followed by 500 mg (immediate-release formulation) orally to complete a 7- to 10-day course of therapy Comment: Extended-release formulations should be taken on an empty stomach. Uses: -Treatment of mild community acquired pneumonia due to Chlamydophila pneumoniae, Haemophilus influenzae, Mycoplasma pneumoniae, or Streptococcus pneumoniae in patients appropriate for oral therapy -Treatment of community-acquired pneumonia due to C pneumoniae, H influenzae, Legionella pneumophila, Moraxella catarrhalis, M pneumoniae, or S pneumoniae in patients who require initial IV therapy Community-acquired pneumonia: Oral: -Immediate-release: 500 mg orally as a single dose on day 1, followed by 250 mg orally once a day on days 2 to 5 -Extended-release: 2 g orally once as a single dose Parenteral: 500 mg IV once a day as a single dose for at least 2 days, followed by 500 mg (immediate-release formulation) orally to complete a 7- to 10-day course of therapy Comment: Extended-release formulations should be taken on an empty stomach. Uses: -Treatment of mild community acquired pneumonia due to Chlamydophila pneumoniae, Haemophilus influenzae, Mycoplasma pneumoniae, or Streptococcus pneumoniae in patients appropriate for oral therapy -Treatment of community-acquired pneumonia due to C pneumoniae, H influenzae, Legionella pneumophila, Moraxella catarrhalis, M pneumoniae, or S pneumoniae in patients who require initial IV therapy Community-acquired pneumonia: Oral: -Immediate-release: 500 mg orally as a single dose on day 1, followed by 250 mg orally once a day on days 2 to 5 -Extended-release: 2 g orally once as a single dose Parenteral: 500 mg IV once a day as a single dose for at least 2 days, followed by 500 mg (immediate-release formulation) orally to complete a 7- to 10-day course of therapy Comment: Extended-release formulations should be taken on an empty stomach. Uses: -Treatment of mild community acquired pneumonia due to Chlamydophila pneumoniae, Haemophilus influenzae, Mycoplasma pneumoniae, or Streptococcus pneumoniae in patients appropriate for oral therapy -Treatment of community-acquired pneumonia due to C pneumoniae, H influenzae, Legionella pneumophila, Moraxella catarrhalis, M pneumoniae, or S pneumoniae in patients who require initial IV therapy Immediate-release: 500 mg orally as a single dose on day 1, followed by 250 mg orally once a day on days 2 to 5 Use: Treatment of pharyngitis/tonsillitis caused by Streptococcus pyogenes as an alternative to first-line therapy in patients who cannot use first-line therapy IDSA Recommendations: Immediate-release: Individuals with penicillin allergy: 12 mg/kg orally once a day -Maximum dose: 500 mg/day -Duration of therapy: 5 days Use: Treatment of Group A streptococcal pharyngitis Immediate-release: 500 mg orally once a day for 3 days Extended-release: 2 g orally once as a single dose Comment: Extended-release formulations should be taken on an empty stomach. Use: Treatment of mild to moderate acute bacterial sinusitis due to H influenzae, M catarrhalis, or S pneumoniae Immediate-release: 500 mg orally as a single dose on day 1, followed by 250 mg orally once a day on days 2 to 5 Use: Treatment of mild to moderate uncomplicated skin and skin structure infections due to Staphylococcus aureus, Streptococcus pyogenes, or Streptococcus agalactiae IDSA and NIH Recommendations: Immediate-release: Patients greater than 45 kg: 500 mg orally on day 1, then 250 mg orally once a day on days 2 through 5 Patients less than 45 kg: 10 mg/kg orally on day 1, then 5 mg/kg orally once a day for 4 additional days Alternative therapy for Bartonella infections (not endocarditis or central nervous system infections): 500 mg orally once a day for at least 3 months Uses: -Treatment of bacillary angiomatosis and cat scratch disease -Alternative therapy for Bartonella infections Gonococcal urethritis and cervicitis: Immediate-release: 2 g orally once Use: Treatment of mild to moderate urethritis and cervicitis due to Neisseria gonorrhoeae US Centers for Disease Control and Prevention (CDC) Recommendations: Immediate-release: -Recommended regimen: 1 g orally once as a single dose plus ceftriaxone -Alternative regimen: 1 g orally once as a single dose plus cefixime Comments: -The alternative regimen may be used for uncomplicated infections if ceftriaxone is unavailable. -Arthritis and arthritis-dermatitis syndrome may be treated with 1 g orally once plus cefotaxime OR ceftizoxime. Uses: -Uncomplicated gonococcal infections of the pharynx, cervix, urethra, and rectum -Treatment of gonococcal conjunctivitis -Treatment of arthritis and arthritis-dermatitis syndrome caused by disseminated gonococcal infection -Treatment of gonococcal meningitis and endocarditis Non-gonococcal urethritis and cervicitis: -Immediate-release: 1 g orally once Comment: A 1 g oral dose given once a week for 3 weeks may be effective in the treatment of lymphogranuloma venereum due to Chlamydia trachomatis. Macrólido con acciones y usos muy similares a la eritromicina. Se excreta en muy pequeña cantidad en la leche materna (Sutton 2015, Salman 2015, Kelsey 1994) y no se han observado problemas en lactantes cuyas madres la tomaban (Goldstein 2009). Diversas sociedades médicas y consensos de expertos consideran seguro el uso de esta medicación durante la lactancia (Butler 2014, Kong 2013, Khrianin 2010, Chen 2010, Goldstein 2009, Mahadevan 2006, Bar-Oz 2003, Chin 2001). Algunos autores han relacionado la exposición temprana (primeros 15 días de vida) a macrólidos (en especial la Eritromicina) con la aparición de estenosis hipertrófica de píloro (Lund 2014), incluso a través de la leche materna (Maheshwai 2007, Sørensen 2003), pero otros no y menos para la Azitromicina (Goldstein 2009, Maheshwai 2007). Tener en cuenta la posible negatividad de cultivos en lactantes febriles cuyas madres toman antibióticos, así como la posibilidad de gastroenteritis por alteración de la flora intestinal Puede consultar abajo la información de este producto relacionado: Las recomendaciones de e-lactancia las realizan pediatras y farmacéuticas de APILAM y están basadas en publicaciones científicas recientes. Estas recomendaciones no pretenden reemplazar la relación con su médico, sino complementarla. Tu aportación es fundamental para que este servicio siga existiendo. Necesitamos la generosidad de personas como tú que creen en las bondades de la lactancia materna.

    Azithromycin for infants

    Azithromycin 500mg Tablets - Summary of Product Characteristics., Azithromycin - Wikipedia

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  5. Azithromycin for bacterial infections This leaflet is about the use of azithromycin for the treatment of bacterial infections.

    • Azithromycin for bacterial infections Medicines for Children.
    • Azithromycin Zithromax Antibiotic Side Effects & Dosage.
    • Use and safety of azithromycin in neonates a systematic review.

    Infants who receive azithromycin within the first days of life have an 8-fold increase in risk of developing hypertrophic pyloric stenosis, report. BACKGROUND AND OBJECTIVE Use of oral erythromycin in infants is associated with infantile hypertrophic pyloric stenosis IHPS. The risk with azithromycin. Sep 10, 2014. WASHINGTON -- Infants who received azithromycin Zithromax in the early days of life were at an increased risk for developing infantile.

     
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