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Tretinoin is thought to act by enhancing skin epithelial cell proliferation and accelerating epithelial differentiation; it also has anti-inflammatory properties. Acne is often associated with puberty when a surge of androgen hormones can over stimulate the sebaceous glands (oil producing glands in hair follicles). Skin cells that are shed from the lining of the hair follicle become trapped in sebum forming a plug below the surface of the skin, clogging the pores, which then attracts bacteria, so that the clogged pores become infected and inflamed, causing an acne outbreak. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Tretinoin belongs to a class of medications called retinoids. Read the Patient Information Leaflet if one is available from your pharmacist. Consult your doctor or pharmacist if you have questions. Gently clean the affected skin with a mild or soapless cleanser and pat dry. 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