Do not stop taking this medication without consulting your doctor. Some conditions may become worse when you suddenly stop this drug. Some people who have suddenly stopped taking similar drugs have had chest pain, heart attack, and irregular heartbeat. If your doctor decides you should no longer use this drug, he or she may direct you to gradually decrease your dose over 1 to 2 weeks. When gradually stopping this medication, it is recommended that you temporarily limit physical activity to decrease strain on the heart. Get medical help right away if you develop chest pain/tightness/pressure, chest pain spreading to the jaw/neck/arm, unusual sweating, trouble breathing, or fast/irregular heartbeat. Show More This medication is a beta-blocker used to treat chest pain (angina), heart failure, and high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. If you were previously taking metoprolol succinate, and your doctor has now switched your prescription to metoprolol tartrate, or vice versa, you may be wondering what the differences are. Read on to learn more about the two different types of metoprolol. Is there an advantage to taking metoprolol tartrate vs. The primary difference between metoprolol succinate and metoprolol tartrate is the length of time that the drugs stay in your bloodstream. Metoprolol succinate will stay in a person's bloodstream for 24 complete hours. This means that the medication is a once per day pill. Metoprolol tartrate, on the other hand, will not stay in the bloodstream as long and thus needs to be taken at regular intervals. One potential complication is that while people recognize the need to keep from taking a double dose of a once per day pill, someone who has missed a dose of metoprolol succinate may be tempted to double up to try and catch up. This is dangerous and could lead to a potential overdose. It seems like it would be more convenient to just have a once per day pill, but both serve a purpose. Order kamagra gel Can you buy viagra over the counter in northern ireland Viagra overnight shipping usa Answers - Posted in metoprolol, metoprolol succinate er - Answer No its not ok, because the dosing is different. The tartrate is short. Metoprolol succinate is an extended-release version of metoprolol, so it remains in the bloodstream and controls blood pressure for a full 24 hours. Metoprolol tartrate does not stay in the bloodstream for 24 hours. Non-acute setting or maintenance Metoprolol tartrate immediate-release 25 to 100 mg PO twice daily. Metoprolol succinate extended-release 25 to 200 mg. The key difference between tartrate and succinate is that succinate is derived from the succinic acid and tartrate is derived from the tartaric acid. The major commercial source of tartrate is the wine industry. These two chemical substances are widely used in the beverage industry and drug manufacturing. Succinate can donate electrons for the chemical reactions that need electrons. Metoprolol succinate and metoprolol tartrate are different drug molecules which treat high blood pressure. Research articles show that succinate inhibits HIF-α prolyl hydroxylase and links TCA (tricarboxylic acid) cycle dysfunction to oncogenesis.. A recent research has proved that succinate increases the interleukin-1β production during inflammation acting as an intermediate. According to the outcomes of that study, lipopolysaccharides highly increase the level of succinate in the TCA cycle. Succinate is produced through the Glutamine – dependent aneplerosis and the GABA shunt pathway. Succinate dehydrogenase is a main enzyme of the TCA cycle. So, succinate links TCA cycle dysfunction to oncogenesis. Metoprolol succinate and metoprolol tartate belong to a class of drugs known as beta-blockers. These drugs treat high blood pressure and other heart conditions by blocking the effects of adrenaline on the heart. Metoprolol tartrate treats high blood pressure (hypertension) and angina (chest pain). Doctors also prescribe metoprolol tartrate for people who have had heart attacks. Metoprolol succinate treats hypertension, heart failure and angina. Metoprolol succinate is an extended-release version of metoprolol, so it remains in the bloodstream and controls blood pressure for a full 24 hours. Metoprolol tartrate does not stay in the bloodstream for 24 hours. Metoprolol tartrate to succinate Hemodynamic comparison of twice daily metoprolol tartrate with., Difference Between Metoprolol Succinate and Metoprolol Tartrate. Canada drugAmoxicillin grapefruit Feb 28, 2018. The beta-blockers metoprolol tartrate and metoprolol succinate sound alike and treat some of the same conditions, but they're different drugs. Metoprolol Tartrate vs. Metoprolol Succinate A Comparison - Healthline. Metoprolol - American College of Cardiology. Metoprolol Tartrate and Metoprolol Succinate – Safety Medical. Find patient medical information for Metoprolol Tartrate Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user. Download Citation on ResearchGate On Mar 1, 2003, P. Müller-Marhenke and others published Differences between metoprolol tartrate and succinate. TOPROL-XL, metoprolol succinate, is a beta 1-selective cardioselective adrenoceptor blocking agent, for oral administration, available as extended-release tablets. TOPROL-XL has been formulated to provide a controlled and predictable release of metoprolol for once-daily administration.