Tamoxifen fertility

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  1. Corvinus Guest

    Tamoxifen fertility


    Many premenopausal women who undergo chemotherapy will experience chemotherapy-induced amenorrhea (the absence of your menstrual period), premature menopause or infertility. Research has indicated that treatment-related menopause is less common in women younger than age 35 and is often related to the type of chemotherapy drugs used, the dosage of the drugs, and the patient’s age. Most premenopausal women will stop menstruating at least temporarily during or following chemotherapy. While they may have symptoms of menopause, we avoid using the term “menopause” as many regain ovarian function even a few years later and could even get pregnant while not menstruating. Instead, many doctors nowadays prefer to use the term “chemotherapy-induced amenorrhea” or CIA. Although the data are limited, there is currently no evidence to suggest that pregnancy after breast cancer increases your chance of recurrence. It is often recommended to wait a few years after the completion of all treatment (this includes tamoxifen) to allow your body to recuperate. A series of blood tests to check the levels of a hormone called FSH (follicle stimulating hormone) can be taken. To check if your ovaries are working, your specialist will ask about your periods, whether they’ve started again and whether you have any menopausal symptoms. After your treatment has finished, there’s no totally reliable way of checking how it has affected your fertility. Finding support If you're planning to become pregnant after breast cancer treatment, your specialist team will discuss your fertility with you. The results of these can show whether you have gone through the menopause. Sometimes a blood test will also be taken to check the level of a hormone called AMH (anti-mullerian hormone) as this may give more accurate information about how your ovaries are working. An ultrasound scan of the ovaries may also be helpful and is offered in some fertility centres.

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    Tamoxifen is used as an alternative to clomid, it is often less expensive and may cause less thinning of the endometrial lining. Studies suggest that it has the. Ovulation inductions are oral and injectable medication fertility treatments that. Letrozole and tamoxifen are FDA approved to treat breast cancer but also. Why is the breast cancer drug, Tamoxifen, prescribed for infertility?

    There are also some less common but more serious side-effects - tell your doctor about any unusual vaginal bleeding, any pains in your leg or breathlessness, and any allergic-type reactions. The most common unwanted side-effects are hot flushes, and vaginal discharge and itchiness. Treatment options for breast cancer include surgery, chemotherapy, radiotherapy and hormone treatment. Often a combination of two or more of these treatments is used. Some breast cancers need the female hormone oestrogen to grow. The cells of these cancers have receptors on their surface that oestrogen can attach to and are called 'hormone receptor-positive' cancers. Tamoxifen works by blocking the receptors and this prevents oestrogen from reaching cancer cells, stopping them from growing. Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. Tamoxifen is an orally administered medication which is one of the most important drugs used in the treatment of breast cancer around the world. Because of its importance, and the prevalence of breast cancer around the globe, Tamoxifen is included in the WHO's List of Essential Medicines, those which are considered absolutely necessary to provide primary care to patients. Tamoxifen is a medication which limits the activity of Estrogen in the breast tissue. When Tamoxifen is taken, it is broken down into a compound known as 4-hydroxytamoxifen, which then travels through the body producing effects dependent upon where it is. Tamoxifen is considered most valuable because of its effect on breast tissue, but it also impacts processes in other areas of the body, such as the endometrium. In this area of the body, Tamoxifen encourages Estrogenic activity, whereas in the breast tissue it significantly reduces the effects of Estrogen upon breast tissue. Because Tamoxifen impacts Estrogen activity differently depending upon the area of the body, it is referred to as a Selective Estrogen-Receptor Molecule. It is highly effective at treating breast cancer, and the primary form of Hormone Therapy for female patients with Estrogen Receptor Positive breast cancer that have not yet reached menopause. Breast cancer treatment depends upon the type of tissue that is malfunctioning.

    Tamoxifen fertility

    Impact of tamoxifen therapy on fertility in breast cancer survivors, Ovulation Induction Treatment Tennessee Reproductive Medicine

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  5. Apr 21, 2005. clomiphene citrate, ovulation induction, pregnancy, tamoxifen. method of ovulation induction in couples with anovulatory infertility since its.

    • Comparison of tamoxifen and clomiphene citrate for ovulation..
    • Tamoxifen for Infertility - University Reproductive Associates.
    • Young Breast Cancer Patients Avoiding Tamoxifen Because of..

    BACKGROUND Clomiphene citrate is commonly used for ovulation induction in women with anovulatory infertility. Tamoxifen may be a better choice in some patients who fail to either ovulate or conceive with clomiphene due to its favorable effect on the cervical mucus and endometrium. Tamoxifen has had a major impact on reducing the risk of breast cancer recurrences, but many younger women are either not starting treatment or are. Patients were assigned to two comparable groups group A n=122 was treated with 10 mg tamoxifen twice daily for a period of 3 months and group B n=117.

     
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