It is a prescription-only drug approved for the treatment of chronic musculoskeletal pain and chronic low back pain, which can be caused by conditions such as osteoarthritis. Subsequently, it was also approved for treatment of anxiety, pain caused by diabetic neuropathy, and pain caused by fibromyalgia before gaining FDA approval for chronic musculoskeletal pain in 2010. Food and Drug Administration (FDA) in 2004 for major depressive disorder. Cymbalta increases the action of serotonin and norepinephrine, which are natural neurotransmitters produced by the body. This effect of Cymbalta alleviates depression and anxiety and decrease pain signals in the brain, spinal cord, and nerves. It has also been suggested that Cymbalta could reduce inflammation or oxidative damage, but these theories have not been proven at this time. Prior to the approval of Cymbalta for musculoskeletal pain, several double-blind, placebo-controlled, randomized clinical trials confirmed that study participants taking Cymbalta had significantly greater pain reduction than participants taking a placebo. Since its approval, more recent studies have shown that Cymbalta reduces chronic musculoskeletal pain and that it is well tolerated. Duloxetine belongs to the class of medications called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). It is used to treat depression and generalized anxiety disorder. It can also be used to treat diabetes-related nerve pain, fibromyalgia, chronic low back pain, and chronic pain from osteoarthritis of the knee. For depression and anxiety, duloxetine works by affecting the balance of chemicals in the brain and other parts of the body. For certain types of pain, duloxetine works by affecting the balance of chemicals in the brain and spinal cord that are involved in the experience of pain. This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. Clomid for men reviews Where can i buy augmentin Cheap kamagra paypal uk Dec 12, 2013. Duloxetine, the generic drug for Cymbalta, was just recently approved. products, and that all generics have to pass the same quality regime. Nov 29, 2018. Cymbalta duloxetine hydrochloride is a selective serotonin and. the medication or experiences the same degree of pain relief from it; some. Duloxetine 30mg and 60mg Gastro-resistant Capsules, hard - Patient Information Leaflet PIL by Accord-UK Ltd Cymbalta (duloxetine) is a selective serotonin and norepinephrine reuptake inhibitor antidepressant (SSNRI). Duloxetine affects chemicals in the brain that may be unbalanced in people with depression. Cymbalta is used to treat major depressive disorder in adults. It is also used to treat general anxiety disorder in adults and children who are at least 7 years old. Cymbalta is also used in adults to treat fibromyalgia (a chronic pain disorder), or chronic muscle or joint pain (such as low back pain and osteoarthritis pain). Cymbalta is also used to treat pain caused by nerve damage in adults with diabetes (diabetic neuropathy). Do not take Cymbalta within 5 days before or 14 days after you have used a MAO inhibitor, such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine, or methylene blue injection. In some cases, they may not be available in all strengths or forms as the brand-name drug. Duloxetine oral capsule is available as the brand-name drugs Cymbalta and Irenka. Generic drugs usually cost less than the brand-name version. Duloxetine oral capsule is used to treat: Duloxetine belongs to a class of drugs called serotonin-norepinephrine reuptake inhibitors (SNRIs). It works by balancing chemicals in your brain that cause depression and anxiety. By balancing these chemicals, this drug also helps inhibit pain signals from your nerves to your brain. Duloxetine oral capsule can cause sleepiness or may affect your ability to make decisions, think clearly, or react quickly. You shouldn’t drive, use heavy machinery, or do other dangerous activities until you know how it affects you. In adults, the more common side effects of duloxetine can include: Call your doctor right away if you have serious side effects. 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