Azithromycin wikipedia

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    Azithromycin wikipedia


    Azithromycin is an azalide, a subclass of macrolide antibiotics. Azithromycin (brand names Zithromax® in Italy, The United Kingdom, The United States, Portugal and Belgium; ATM® in India, Vinzam® / Zitromax® in Spain; Zmax®; Sumamed®; Aztrin®, Zitrocin®, Azibiot®, Azifine®) is one of the world's best-selling antibiotics, and is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring, thus making the lactone ring 15-membered. Azithromycin is used to treat certain bacterial infections, most often bacteria causing middle ear infections, tonsillitis, throat infections, laryngitis, bronchitis, pneumonia and sinusitis. It is also effective against certain sexually transmitted infectious diseases, such as non-gonococcal urethritis and cervicitis. Recent studies have also indicated it to be effective against late-onset asthma, but these findings are controversial and not widely accepted as of yet. Azithromycin's name is derived from the azane-substituent and erythromycin. Its accurate chemical name is (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13- [(2,6-dideoxy-3-C-methyl-3-O-methyl -α-L-ribo-hexopyranosyl)oxy]-2-ethyl- 3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl -11-3,4,6-trideoxy-3-(dimethylamino) -β-D-xylo-hexopyranosyloxy]-1-oxa- 6-azacyclopentadecan-15-one. Текст данной статьи практически полностью повторяет инструкцию по применению лекарственного средства, предоставляемую его производителем. Это нарушает правило о недопустимости инструкций в энциклопедических статьях. Кроме того, предоставленные данные могут быть недостаточно объективными и достоверными (особенно в части эффективности и безопасности препарата). Для соблюдения нейтральности изложения необходимо переработать данную статью, основываясь на независимых авторитетных источниках информации. гранулы для приготовления суспензии для приёма внутрь; капсулы; лиофилизат для приготовления раствора для инфузий; субстанция-порошок; таблетки, покрытые оболочкой; порошок для приготовления суспензии для приёма внутрь; порошок для приготовления суспензии пролонгированного действия для приёма внутрь. «Азивок», «Азимед», «Азимицин», «Азитрал», «Азитрокс», «Азитромицин», «Азитромицина дигидрат», «Азитроцин», «Азит Рус», «Азицид», «Веро-Азитромицин», «Зетамакс ретард», «Зи-Фактор», «Зитноб», «Зитролид», «Зитроцин», «Сумазид», «Сумаклид», «Сумамед», «Сумамецин», «Сумамокс», «Суматролид», «Тремак-Сановель», «Хемомицин», «Экомед». Азитромици́н является полусинтетическим антибиотиком, первым представителем подкласса азалидов, несколько отличающихся по структуре от классических макролидов.

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    Antacids containing aluminum or magnesium decreased peak azithromycin blood level Arrhythmias such as amiodarone, quinidine increased risk of life-threatening arrhythmias Carbamazepine, cyclosporine, digoxin, dihydroergotamine, ergotamine, hexobarbital, phenytoin, theophylline, triazolam increased blood levels of these drugs Сумамед Sumamed. Антибиотик широкого спектра действия. Антибиотик-азалид, представитель новой подгруппы макролидных антибиотиков. При создании в очаге воспаления высоких концентраций оказывает бактерицидное действие. Azithromycin is a macrolide antibiotic that is widely used in the management of bacterial infections, including pneumonia, chlamydia, streptococcal pharyngitis.

    Among adolescents with urogenital chlamydia, is azithromycin similar to doxycycline for the treatment of chlamydia infection? Among adolescents being treated for urogenital chlamydia infection, azithromycin treatment was 97% effective compared to 100% effectiveness of doxycycline. Azithromycin was not deemed to be noninferior to doxycycline. Treatment response for both groups was high and small difference in treatment response might be offset by the comparative ease of administration of single dose of azithromycin versus lower adherence of the twice daily, 7 days course of doxycycline. Urogenital chlamydia infection is the most frequently reported sexually transmitted infection in the United States and worldwide. With a growing prevalence, efforts to prevent and control chlamydia infections have been high and the efficacy of the current treatment guidelines have been at the foundation of the chlamydia control programs. The Centers for Disease Control and Prevention (CDC) recommends oral administration of azithromycin 1 gram in a single dose or doxycycline 100 mg twice daily for 7 days for the treatment of C. These guidelines are based off of a meta-analysis of 12 randomized clinical trials, where the goal of was to evaluate the efficacy and tolerance of azithromycin versus doxycycline for genital chlamydial infections. It is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring, thus making the lactone ring 15-membered. Azithromycin is used to treat or prevent certain bacterial infections, most often those causing middle ear infections, tonsillitis, throat infections, laryngitis, bronchitis, pneumonia, Typhoid, and sinusitis.(2R,3S,4R,5R,8R,10R,11R,12S,13S,14S)-11-((2S,3R,4S,6R)- 4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)- 2-ethyl-3,4,10-trihydroxy-13-((2S,4R,5S)-5-hydroxy- 4-methoxy-4-methyltetrahydro-2H-pyran-2-yloxy)- 3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one A team of researchers at the Croatian pharmaceutical company Pliva, Gabrijela Kobrehel, Gorjana Radobolja-Lazarevski and Zrinka Tamburašev led by Dr. It was patented in 1981, and was later found by Pfizer's scientists while going through patent documents. In 1986 Pliva and Pfizer signed a licensing agreement which gave Pfizer exclusive rights for the total parka Important safety and tolerability AZITHROMYCIN will be TARGETED and AZITHROMYCIN is a problem--as long-term sperm of oral prednisone. The 250 mg tablets are often dispensed in packages of six and commonly referred to as a "Z-Pak," whereas the 500 mg tablets are commonly available commercially in a pack of three tablets, or "Tri-Pak," intended as a three-day treatment. Pfizer brand-name (e.g., Zithromax) azithromycin tablets are mottled pink, unscored, film-coated, modified-oval-shaped tablets containing azithromycin monohydrate equivalent to 250 mg or 500 mg azithromycin and the following inactive ingredients: butylated hydroxytoluene, calcium phosphate, carmine, colloidal silicon dioxide, FD&C red # 40 lake, FD&C yellow # 6 lake, hypromellose (2910, 15c P), lactose monohydrate, magnesium stearate, pregelatinized starch, sodium lauryl sulfate, talc, titanium dioxide and triacetin. Tablet Each pink, modified capsular-shaped, film-coated tablet, engraved "N" on one side and "250" on the other side, contains azithromycin monohydrate hemiethanolate equivalent to azithromycin 250 mg. Azithromycin is sold under brand names APO-Azithromycin and Co Azithromycin in Canada; Zithromax in Finland, Italy, the United Kingdom, the United States, Australia, Portugal, South Africa, Canada, Thailand, Malaysia, Lebanon and Belgium; Hemomicin in Serbia; Zithromac in Japan; Vinzam/Zitromax in Spain; Zmax; Sumamed in Bulgaria, Croatia, the Czech Republic, the Russian Federation and Slovakia; Azitrox in Czech Republic and Romania; Amixef in Peru; ATM, Aztrin, Azigard, Zitrocin, Azibiot, Azifine, Azi Cip, Azi Sandoz, Aziswift, AZORTA & AZEE, Azithral, ZADY in India; Azithromycin tablets contains soya lecithin which might be a source of soya protein and should therefore not be taken in patients allergic to soya or peanut due to the risk of hypersensitivity reactions. In a study of adults receiving a standard regimen of 500 mg on day 1 followed by 250 mg on days 2-5, the maximum concentration was 0.24 mcg/ml, with a time to achieve maximum concentration of 3.2 hours and an average area under the concentration curve (AUC) of 2.1 mcg·hr/ml.

    Azithromycin wikipedia

    Azithromycin definition of azithromycin by Medical, Сумамед — Медицинская википедия

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  6. Azithromycin is an azalide, a type of macrolide antibiotic. It works by decreasing the production of protein, thus stopping bacterial growth. Azithromycin is on the World Health Organization’s List of Essential Medicines, the most important medications needed in a basic 4 ___ system. It is available as a generic medication and is sold under.

    • Azithromycin Jan 16, 2017 - Target Health.
    • Azithromycin Health and Medicine Wiki FANDOM powered by Wikia.
    • Azithromycin Monohydrate C38H74N2O13 - PubChem.

    Azithromycin Azithromycin Systematic IUPAC name 9-deoxy-9a-aza-9a-methyl-9a- homoerythromycin A Identifiers CAS number 83905-01-5 ATC code J01FA10 PubChem. Азитромицин Azithromycin. Азитромици́н является полусинтетическим антибиотиком, первым представителем подкласса азалидов, несколько отличающихся по структуре от. Azithromycin and clarithromycin are better than erythromycin at reaching the lungs and respiratory tractNew World Encyclopedia writers and editors rewrote and completed the Wikipedia article in.

     
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