Metformin overdose side effects

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  1. Max314 Well-Known Member

    Metformin overdose side effects


    Rarely, too much metformin can build up in the body and cause a serious (sometimes fatal) condition called lactic acidosis. Lactic acidosis is more likely if you are an older adult, if you have kidney or liver disease, dehydration, heart failure, heavy alcohol use, if you have surgery, if you have X-ray or scanning procedures that use iodinated contrast, or if you are using certain drugs. For some conditions, your doctor may tell you to stop taking this medication for a short time. Stop taking this medication and get medical help right away if you have any symptoms of lactic acidosis, such as unusual tiredness, dizziness, severe drowsiness, chills, blue/cold skin, muscle pain, fast/difficult breathing, slow/irregular heartbeat, or stomach pain with nausea/vomiting/diarrhea. Show More Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb. Read the Patient Information Leaflet if available from your pharmacist before you start taking metformin and each time you get a refill. The immediate-release tablet is available as the brand-name drug Glucophage. Metformin oral tablet comes in two forms: immediate-release and extended-release. The extended-release tablet is available as the brand-name drugs Glucophage XR, Fortamet, and Glumetza. Both tablet forms are also available as generic drugs. Generics usually cost less than brand-name versions. In some cases, they may not be available in all strengths or forms as brand-name drugs. Metformin oral tablets are used to treat high blood sugar levels caused by type 2 diabetes.

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    A review of metformin overdoses reported to poison control centers over a. The most common symptoms following overdose include. An overdose of metformin may cause lactic acidosis. Get emergency medical help if you have any of these symptoms of lactic acidosis weakness, increasing sleepiness, slow heart rate, cold feeling, muscle pain, shortness of breath, stomach pain, feeling light-headed, and fainting. A Metformin has been on the market for many years with a good safety record. As long as you have had no side effects or any kidney or liver problems, then there is no reason why you should not.

    ) is a prescription medication that has been licensed to treat type 2 diabetes. Are you still sure that you want to clear all of you selected topics? As with all medicines, it is possible to take too much metformin. Effects of a metformin overdose will vary depending on a number of factors, including how much metformin was taken and whether it was taken with any other medicines, alcohol, and/or drugs. Princeton, NJ: Bristol-Myers Squibb Company;2006 June. If you choose this option, it cannot be undone, and you'll need to choose at least new topic to continue using your Health Savvy programs. Press "Continue" button below to begin selecting your Health Savvy topic(s). Remember, you need at least one selected topic to use Health Savvy. Click In order for us to create your customized Health Savvy programs, we need a little more information about the health topic(s) that you are interested in. Jacksonville, FL: Ranbaxy Pharmaceuticals, Inc.;2004 May. Site users seeking medical advice about their specific situation should consult with their own physician. Metformin is a biguanide used to treat type 2 diabetes mellitus and most commonly prescribed oral hypoglycemic agent. Metformin is now also used to treat polycystic ovary syndrome and some malignancies. Despite a good safety profile in a majority of patients with diabetes, the risk of metformin-associated lactic acidosis is genuine when safety guidelines are ignored. Overdoses with metformin are rare, but may result in serious consequences. Case reports and small case series of serious toxicity from metformin overdosage can be found in the medical literature, often with the portrayal of extracorporeal methods for the management of the subsequent severe lactic acidosis. Lactic acidosis can defined as a metabolic acidosis with a blood p H less than 7.35 and a serum lactate more than 2 mmol per liter. It can occur either with therapeutic metformin dosing (which is rare) or in overdose situations.

    Metformin overdose side effects

    MALA Metformin-Associated Lactic Acidosis California Poison., How much Metformin is too much? Can you overdose. -

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  4. Metformin is a prescription drug used to treat type 2 diabetes. Learn about side effects, drug interactions, dosages, warnings, and more.

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    Jan 6, 2013. Introduction Metformin is a commonly used treatment modality in type 2 diabetes mellitus, with a well documented side effect of lactic acidosis. Metformin oral tablet can cause mild or serious side effects. The following list contains some of the key side effects that may occur while taking metformin. NHS medicines information on metformin – what it's used for, side effects. An overdose of a large number of metformin tablets can cause serious health.

     
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    Tamoxifen has rarely caused very serious (possibly fatal) strokes, blood clots in the lungs/legs, and cancer of the uterus. If you are taking tamoxifen to reduce the risk of breast cancer, or if your cancer is limited to the milk ducts (ductal carcinoma in situ-DCIS), then discuss the benefits and risks of taking this medication with your doctor. However, if you are taking tamoxifen to treat breast cancer, then the benefits of taking tamoxifen are greater than the risks of side effects. Get medical help right away if you develop symptoms of a stroke or blood clots in the lungs/legs, such as weakness on one side of the body, slurred speech, sudden vision changes, confusion, shortness of breath, chest pain, or calf pain/swelling. Tell your doctor right away if you develop symptoms of cancer of the uterus, such as unusual changes in your monthly period (e.g., amount or timing of bleeding), unusual vaginal discharge, or pain/pressure below your "belly button" (navel). Show More Tamoxifen is used to treat breast cancer. It is also used to reduce the chances of breast cancer in high-risk patients. This medication can block the growth of breast cancer. Tamoxifen - Handling and Storage Tamoxifen Tamoxifen Preparation - Memorial Sloan Kettering Cancer Center
     
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