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    On 22 March 2018, the European Medicines Agency (EMA) completed its review of retinoid medicines, and confirmed that an update of measures for pregnancy prevention is needed. In addition, a warning on the possibility that neuropsychiatric disorders (such as depression, anxiety and mood changes) may occur will be included in the prescribing information for oral retinoids (those taken by mouth). Retinoids include the active substances acitretin, adapalene, alitretinoin, bexarotene, isotretinoin, tazarotene and tretinoin. They are taken by mouth or applied as creams or gels to treat several conditions mainly affecting the skin, including severe acne and psoriasis. Some retinoids are also used to treat certain forms of cancer. The review confirmed that oral retinoids can harm the unborn child and must not be used during pregnancy. In addition, the oral retinoids acitretin, alitretinoin and isotretinoin, which are used to treat conditions mainly affecting the skin, must be used in accordance with the conditions of a new pregnancy prevention programme by women able to have children. The word is that Morrisons (LON: MRW) are really keen to get cracking with Ocado who report half yearly results. It’s important we don’t read too much into the results even though losses are expected to be down. But the real news keenly awaited is the partnerships of the …

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    It stimulates cell division and improves the skin by allowing old, damaged skin cells to be removed fast so new ones can present themselves. Doctors prescribe this medicine to treat severe cases of acne when some areas of the skin are also inflamed. Acne is a common condition in adolescents and adults alike. Tretinoin (Vitamin A Acid Cream) is only available on prescription. At dokteronline.com, you do not need a prescription from your GP: our doctor can issue an online prescription after an online consultation. Tretinoin (Vitamin A Acid Cream) can be very effective in treating unattractive skin conditions, such as: Tretinoin improves the skin by allowing old skin cells to be removed fast so new ones can present themselves. Tretinoin opens clogged pores, reduces patches and wrinkles, and heals infected skin. A-Ret Gel 0.1% (Tretinoin) is used as a topical treatment for acne. Some people may also use it for fine wrinkles and its other reported cosmetic benefits in skin aging. It helps to unblock pores on the skin and promote healing and exfoliation on the outer skin layers, while also affecting skin cell growth. Its active ingredient is a topical retinoid similar to vitamin A. A-Ret Gel 0.1% (Tretinoin) is a topical gel that needs to be applied to the affected area in strict compliance with the instructions provided by your doctor. It is also important to ensure that the skin is completely dry, as irritation may occur if the gel is applied to skin that is wet. Allow a minimum of 20 minutes after washing the face before the gel is applied, and avoid washing the treated skin (or applying any cosmetic skincare products to it) for a period of at least one hour after application. Patients are sometimes directed by a doctor to apply the gel once per day, just before bed, or else once every 2 to 3 days. In some cases, a worsening of acne may occur, however, with continued treatment, patients will usually notice an improvement in symptoms.

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    How to cite this URL: Modi AM, Menon DS, Marfatia YS. The androgens testosterone and dihydrotestosterone (DHT) have somewhat different actions. Abstracts from the current global literature: Finasteride and sexual dysfunction. The enzyme 5-alpha reductase inhibitor (5ARI) converts testosterone into DHT. While type I is predominant in liver, type II is predominant in prostate, seminal vesicles, epididymis, hair follicles, and liver. Indian J Sex Transm Dis [serial online] 2017 [cited 2019 Feb 23];0-2. 2017/38/2/200/216987 Finasteride and sexual side effects1. Finasteride is a specific and competitive inhibitor of Type II 5ARI (has a more significant role in pattern hair loss) and has therefore a selective action on hair follicles. This article critically examines the evidence available and makes recommendations as to how a physician should counsel a patient while prescribing the drug. Studies reveal that sexual adverse effects occur at the rates of 2.1%–3.8%, erectile dysfunction being the most common followed by ejaculatory dysfunction and loss of libido which occur early in the therapy and return to normal on stopping or over a time on continuous usage of the drug. A comprehensive review of a total of 73 papers on medical therapies for benign prostatic hyperplasia revealed that finasteride is infrequently associated with problems of ejaculation (2.1%–7.7%), erection (4.9%–15.8%), and libido (3.1%–5.4%). The nocebo effect has an influence in the causation of side effects and suggesting the role of psychological factors. Abstracts from the current global literature Finasteride and sexual. Baldness Remedy Side Effects - Men's Health Finasteride and sexual side effects - NCBI - NIH
     
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