Metformin ppt

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  1. anat555 XenForo Moderator

    Metformin ppt


    The UK Prospective Diabetes Study, a large clinical trial performed in 1980-90s, provided evidence that metformin reduced the rate of adverse cardiovascular outcomes in overweight patients with type 2 diabetes relative to other antihyperglycemic agents. Treatment guidelines for major professional associations including the European Association for the Study of Diabetes, the European Society for Cardiology and the American Diabetes Association, now describe evidence for the cardiovascular benefits of metformin as equivocal. In 2017, the American College of Physicians's guidelines were updated to recognize metformin as the first-line treatment for type-2 diabetes. For example, a 2014 review found tentative evidence that people treated with sulfonylureas had a higher risk of severe low blood sugar events (RR 5.64), though their risk of non-fatal cardiovascular events was lower than the risk of those treated with metformin (RR 0.67). There was not enough data available at that time to determine the relative risk of death or of death from heart disease. study known as the Diabetes Prevention Program, participants were divided into groups and given either placebo, metformin, or lifestyle intervention and followed for an average of three years. Metformin treatment of people at a prediabetes stage of risk for type 2 diabetes may decrease their chances of developing the disease, although intensive physical exercise and dieting work significantly better for this purpose. The intensive program of lifestyle modifications included a 16-lesson training on dieting and exercise followed by monthly individualized sessions with the goals of decreasing weight by 7% and engaging in physical activity for at least 150 minutes per week. The incidence of diabetes was 58% lower in the lifestyle group and 31% lower in individuals given metformin. Among younger people with a higher body mass index, lifestyle modification was no more effective than metformin, and for older individuals with a lower body mass index, metformin was no better than placebo in preventing diabetes. The bladder is a hollow organ in your lower abdomen that stores urine. Bladder cancer occurs in the lining of the bladder. It is the sixth most common type of cancer in the United States. Symptoms include Risk factors for developing bladder cancer include smoking and exposure to certain chemicals in the workplace. People with a family history of bladder cancer or who are older, white, or male have a higher risk. Treatments for bladder cancer include surgery, radiation therapy, chemotherapy, and biologic therapy. Biologic therapy boosts your body's own ability to fight cancer.

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    Metformin by Dr Sarma Author Dr Sarma Last modified by. Metformin History Slide 26 Slide 27 Slide 28 Metformin Metformin Slide 31 Slide 32 Slide 33 Slide 34. Nov 12, 2015. Metformin PowerPoint. 1. By Meredith Ashley Metformin; 2. › Prevalence – Affects 24 million people in the United States › Pathophysiology. First, metformin, if not contraindicated and if tolerated, is the preferred initial pharmacological agent for type 2 diabetes. Metformin has a long-standing evidence base for efficacy and safety, is inexpensive, and may reduce risk of cardiovascular events. CLICK

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    Metformin ppt

    Metformin by Dr Sarma - PowerPoint PPT Presentation, Metformin PowerPoint - SlideShare

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  4. The Diabetes PowerPoint Template is a special presentation theme for medical professionals. The individuals who are directly and indirectly involve in treatment of diabetes can use this template.

    • Diabetes PowerPoint Template - SlideModel.
    • PowerPoint Presentation.
    • PowerPoint Presentation - Diabetes Care - American Diabetes..

    Metformin. SU. TZD. FDA mandate. CVOT interpretation. 4. CVOT interpretation. Evolution of T2D agents. Adapted from 1. Kirby. Br J Diabetes Vasc Dis 2012. Metformin only. n = 513. 14.5 months. Sulfonylurea only. n = 3394. 20.5 months. Length of time between first monotherapy HbA1c 8.0% and switch/addition in. Metformin in Diabetes/IGT 1. Metformin is documented to reduce CV events and mortality in Diabetes. 1. Metformin is known to prevent CV events in diabetic patients with cardiac disease undergoing intervention 2. Metformin is known to prevent onset of diabetes in patients with IGT 26.

     
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    Fluconazole is indicated in the treatment of mycoses caused by Candida, Cryptococcus and other susceptible yeast, in particular: 1. The treatment of partners who present with symptomatic genital candidiasis should be considered. Prevention of fungal infections in patients predisposed to such infections as a result of chemotherapy or radiotherapy, including bone transplant patients. Dermatomycosis, including infections such as Tinea pedis, Tinea corporis, Tinea cruris, Tinea versicolor. Mucosal candidiasis: These include oropharyngeal candidiasis, oesophageal, non-invasive bronchopulmonary infections, candiduria, mucocutaneous candidiasis and chronic atrophic oral candidiasis (denture sore mouth). Fluconazole is not indicated for nail infections and tinea capitis. Consideration should be given to official guidance on the appropriate use of antimycotic agents. Both normal hosts and immunocompromised patients may be treated. Before initiating treatment, samples should be taken for microbiological analysis and the suitability of the therapy should be subsequently confirmed (see sections 4.2 and 5.1) In some patients with severe crytococcoal meningitis, the mycological response during fluconazole treatment may be slower that during other treatments (see section 4.4) The daily dose of fluconazole will depend on the nature and severity of the fungal infection. 2 Systemic candidiasis (including disseminated deep infections and peritonitis). Acute cryptococcal meningitis in adults, including patients with AIDS, transplanted patients or other patients with other causes of immunosuppression. Most cases of vaginal candidiasis respond to a single dose treatment. The treatment of those types of infection requiring multiple doses of the drug should be continued until the clinical parameters or laboratory tests indicate that the active fungal infection has subsided. An inadequate treatment period may cause relapses of the active infection. Patients with AIDS and cryptococcal meningitis or recurrent oral candidiasis usually require maintenance treatment to prevent relapses. Diflucan Fluconazole Side Effects, Interactions, Warning, Dosage. Safety and Tolerability of Fluconazole in Children - NCBI - NIH Safety and pharmacokinetics of fluconazole in children with.
     
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