Sertraline is used for a number of conditions, including major depressive disorder (MDD), obsessive–compulsive disorder (OCD), body dysmorphic disorder (BDD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder, and social anxiety disorder (SAD). The comparative efficacy of sertraline and TCAs for melancholic depression has not been studied. A 1998 review suggested that, due to its pharmacology, sertraline may be more efficacious than other SSRIs and equal to TCAs for the treatment of melancholic depression. A meta-analysis of 12 new-generation antidepressants showed that sertraline and escitalopram are the best in terms of efficacy and acceptability in the acute-phase treatment of adults with unipolar MDD. Sertraline used for the treatment of depression in elderly (older than 60) patients was superior to placebo and comparable to another SSRI fluoxetine, and TCAs amitriptyline, nortriptyline (Pamelor) and imipramine. Sertraline had much lower rates of adverse effects than these TCAs, with the exception of nausea, which occurred more frequently with sertraline. In addition, sertraline appeared to be more effective than fluoxetine or nortriptyline in the older-than-70 subgroup. placebo in elderly patients showed a statistically significant (that is, unlikely to occur by chance), but clinically very modest improvement in depression and no improvement in quality of life. A meta-analysis on SSRIs and SNRIs that look at partial response (defined as at least a 50% reduction in depression score from baseline) found that sertraline, paroxetine and duloxetine were better than placebo. Description Pharmacology Indications and Usage Contraindications Warnings Precautions Drug Interactions Adverse Reactions Overdose Dosage Supplied (in plain English) Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of Zoloft or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Zoloft is not approved for use in pediatric patients except for patients with obsessive compulsive disorder (OCD). Propranolol for hypertension Duloxetine brand names How to Increase Zoloft Dose. When used properly, Zoloft can greatly improve the quality of life for people suffering from depression, anxiety, panic disorders, and. Communities Depression Taking Zoloft dosing into my own hands. 10.5k Members Taking Zoloft dosing into my own hands. sammons. I have a question about Zoloft dosing. I have been prescribed a dose of 50mg. I am glad that someone else didn't just blindly listen to their doctor about "upping" the zoloft dose. I feel good at 25 mg. Not. I have a question about Zoloft dosing. I have been prescribed a dose of 50mg. I have been taking half of that dose 25mg, of course for about a month now. There are 11 references cited in this article, which can be found at the bottom of the page. She received her Associates Degree in Nursing from Olney Central College in 1987. Calibrating Your Dosage Taking Zoloft Safely Combining Zoloft with Other Medical Therapies Community Q&A11 References When used properly, Zoloft can greatly improve the quality of life for people suffering from depression, anxiety, panic disorders, and other conditions. Zoloft, also known as sertraline, is a selective serotonin reuptake inhibitor (SSRI) drug. If you are currently taking Zoloft, work with both your primary doctor and your therapist to determine a dosage regimen that fits your needs. If you increase your dosage, do so slowly under your doctor’s supervision, and watch out for any possible side effects. Sertraline oral tablet is a prescription drug that’s available as the brand-name drug Zoloft. This drug may be used as part of a combination therapy. In some cases, they may not be available in every strength or form as the brand-name version. This drug is used to treat major depressive disorder, obsessive-compulsive disorder, panic disorder, posttraumatic stress disorder, social anxiety disorder, and premenstrual dysphoric disorder. This means you may need to take it with other medications. This drug belongs to a class of drugs called selective serotonin reuptake inhibitors. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. This drug works by increasing the amount of serotonin, a natural substance in your brain, that helps maintain mental health balance. Zoloft dose for depression Zoloft Dosage Question - Depression/Mental Health - MedHelp, Taking Zoloft dosing into my own hands. - Depression. Where to purchase clomid onlineTadalafil tablets for saleAzithromycin wikipediaBuy accutane cheapFluconazole headache The typical Zoloft dose for adults with depression or OCD is 50 mg once daily. This eMedTV segment explores common Zoloft dosages for a variety of conditions, such as. Zoloft Dosage - Depression Home Page. Taking Zoloft dosing into my own hands. - Depression - MedHelp. Sertraline Full Prescribing Information HealthyPlace. In patients who exhibit a worsening of depression or emerging suicidality. Due to the long elimination half-life of sertraline, dose adjust only at intervals of 1. I have been taking Zoloft Sertraline 50mg for 2 years and it has changed my life. I had severe depression for over 10 years and it was getting worse to. Sertraline Zoloft is an oral medication used to treat major depressive disorder and other disorders. This can improve the symptoms of depression and anxiety.