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    Azithromycin is the last generation antibiotic representing a macrolides group. The drug is very efficient against the overwhelming number of disease-producing microorganisms. Azithromycin decreases the activity of certain cells of disease-producing microbes which develop proteins. Therefore, this antibiotic possesses bactericidal activity. Azithromycin acts on such pathogens as pyogenic streptococcus, pneumococcus, Staphylococcus aureus, Streptococcus type C, F and G, epidermal staphylococcus, Legionella, the causative agent of gonorrhea, as well as the causative agent of syphilis, and so on. Azithromycin is used to treat: Do not treat newborn babies as well as children with dysfunction of kidneys or a liver with Azithromycin. Certain kinds of Azithromycin are not allowed for use by patients under sixteen years. Avoid taking the drug in case of an individual intolerance to macrolides, at heavy kidneys and liver disorders. Azithromycin may be particularly effective against persistent chlamydia. In contrast, doxycycline may not be as effective in treating persistent infection. pelvic inflammatory disease, trachoma) are a mixture of acute and persistent infections. Therefore azithromycin would be more effective for the treatment of chlamydial infections than doxycycline of randomized controlled trials comparing azithromycin with doxycycline for the treatment of genital chlamydia there may be an increased efficacy of up to 3% for doxycycline compared with azithromycin for urogenital chlamydia and about 7% increased efficacy for doxycycline for symptomatic urethral infection in men. Azithromycin is as effective as standard doxycycline in the treatment of adult inclusion conjunctivitis . However, in patients older than 18 years doxycycline is more effective. According to the 2018 research work, pulsed azithromycin (500 mg 1-3 times weekly) provides equivalent efficacy to daily doxycycline in the treatment of moderate or severe acne, a single application of 4% azithromycin cream was 100% protective when applied directly to the tick bite site at the time of tick removal. However, 4% preparation of doxycycline cream provided no protection.

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