Antibiotics are used to treat or prevent some types of bacterial infection. They work by killing bacteria or preventing them from reproducing and spreading. When it comes to antibiotics, take your doctor’s advice. Antibiotics don't work for viral infections such as colds and flu, and most coughs and sore throats. Many mild bacterial infections also get better on their own without using antibiotics. Taking antibiotics when you don’t need them puts you and your family at risk of a longer and more severe illness. People at a high risk of infection may also be given antibiotics as a precaution, known as antibiotic prophylaxis. Read more about when antibiotics are used and why they are not routinely used to treat infections. Although antibiotics have been used in large quantities for some decades, until recently the existence of these substances in the environment has received little notice. It is only in recent years that a more complex investigation of antibiotic substances has been undertaken in order to permit an assessment of the environmental risks they may pose. Within the last decade an increasing number of studies covering antibiotic input, occurrence, fate and effects have been published, but there is still a lack of understanding and knowledge about antibiotics in the aquatic environment despite the numerous studies performed. This review addresses the present state of knowledge concerning the input, occurrence, fate and effects of antibiotics in the environment. It brings up important questions that are still open, and addresses some significant issues which must be tackled in the future for a better understanding of the behavior of antibiotics in the environment, as well as the risks associated with their occurrence. Questions related to resistance in the environment that may be caused by antibiotics will be addressed in the second part. 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