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    , don't worry, take the missed dose as soon as you remember. However, if it is almost time for the next dose (e.g. within 2 or 3 hours), skip the missed dose and go back to your regular dosage schedule. Do not take a double dose to make up for the one that you missed. Most side effects that have been observed were mild to moderate and will generally disappear after a few days to a few weeks of treatment. Check with your doctor if the unwanted effects do not go away during treatment or become bothersome. if you may become pregnant, are pregnant and/or breastfeeding. There is a potential risk of harm to you and the fetus, including risk of fetal malformations. Femara is an antitumor drug that stops the work of the aromatase enzyme. Aromatase is an enzyme that transforms the androgenic hormones into estrogens. The activity of the estrogenic receptors is increased, so that a stimulation of the hormone-dependent tumors grows. Femara blocks the work of aromatase, so that a suppression happens, and then synthesis of estrogen is completely blocked in the tumor tissue and in the peripheral tissues. The everyday use of Femara favors a reduction of the estrogen concentration in 1-2 months (mainly estradiol, estrone and estrone sulfate) in the blood plasma by 80-95% from the default values. At the same time, a blocking of aromatase enzyme does not cause an increase of the concentration of the androgenic hormones. Femara provides an antitumor action but does not favor a reduction of the tumor. The drug stops a progressing of the disease, increases a survival rate without the disease signs within 5 years, reduces a risk of the development of tumor in other parts of the body.

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  8. RegRu Well-Known Member

    News and opinion from members of Partners Asthma Center, a collaboration of allergists and pulmonologists at Brigham and Women's, Massachusetts General, Brigham and Women's Faulkner, and Newton-Wellesley Hospitals and North Shore Medical Center And the dose may have been reduced from its initial large amount to zero in various ways – by 10 mg/day every day or every two days, by 20 mg every 4 days, by inclusion of the low dose of 5 mg/day or not, etc. A recent experiment among more than 300 people with chronic obstructive pulmonary disease (COPD, the chronic obstructive lung disease of cigarette smokers) found that 5 days of prednisone at 40 mg/day was as effective as a two-week course of treatment [Despite the time-honored approach of reducing the dose of prednisone in stepwise decreases – the “steroid taper” -- research has shown that abrupt discontinuation of oral steroids achieves the same asthma control and prevention of recurrences as a slow steroid taper, as long as after the oral steroids you continue preventive treatment with inhaled steroids. In the absence of scientific data, we are free to share with you what we think is a reasonable general approach, acknowledging that other recommendations may someday be found to be just as good or even better (in which case we will change our approach! It then makes most sense to continue treatment at this dose until you are all better or almost all better (as guided by your symptoms or, even better, by finding that your measured peak flow has returned back to its usual value when you are well), and then stop the prednisone or quickly reduce the dose to zero over a few days. Once you are better, we anticipate that you will continue to feel well and maintain good lung function if you continue taking your inhaled steroid and, where possible, avoid the triggers that set off your asthma attack in the first place. Prednisone Tapering Schedule to Reduce Withdrawal - Verywell Health Partners Asthma Center's Asthma Blog A Steroid "Burst" The Asthma Center Education and Research Fund Disease.
     
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