Fluconazole chemical structure

Discussion in 'Walmart Pharmacy Price Check' started by Anton_J, 31-Aug-2019.

  1. bankirfans Well-Known Member

    Fluconazole chemical structure


    Antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole has many advantages over the other antifungal drugs including the option of oral administration. Fluconazole is a first-generation triazole antifungal medication. It differs from earlier azole antifungals (such as ketoconazole) in that its structure contains a triazole ring instead of an imidazole ring. While the imidazole antifungals are mainly used topically, fluconazole and certain other triazole antifungals are preferred when systemic treatment is required because of their improved safety and predictable absorption when administered orally. Fluconazole's spectrum of activity includes most Candida species (but not Candida krusei or Candida glabrata), Cryptococcus neoformans, some dimorphic fungi, and dermatophytes, among others. Common uses include: Fungal resistance to drugs in the azole class tends to occur gradually over the course of prolonged drug therapy, resulting in clinical failure in immunocompromised patients (e.g., patients with advanced HIV receiving treatment for thrush or esophageal Candida infection). albicans, resistance occurs by way of mutations in the ERG11 gene, which codes for 14α-demethylase. These mutations prevent the azole drug from binding, while still allowing binding of the enzyme's natural substrate, lanosterol. glabrata is increasing the rate of efflux of the azole drug from the cell, by both ATP-binding cassette and major facilitator superfamily transporters. Development of resistance to one azole in this way will confer resistance to all drugs in the class. Other gene mutations are also known to contribute to development of resistance.

    Diflucan one dose Fluconazole drug Prednisolone manufacturers

    Download scientific diagram Chemical structure of fluconazole Diflucan. from publication Evaluation of the Drug Treatment and Persistence of. Structure, chemical names, physical and chemical properties, classification. Chemical Names Fluconazole-d4; 1124197-58-5; Biozolene-d4;. DRUG Fluconazole, Help. Entry. D00322 Drug. Name. Fluconazole JP17/USAN /INN; Fluconazole capsules JP17;. Chemical structure group DG00371.

    Fluconazole is only found in individuals that have used or taken this drug. It is a triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS. Fluconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fungal cell membrane, inhibition of its synthesis results in increased cellular permeability causing leakage of cellular contents. Fluconazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and/or phospholipid biosynthesis. Fluconazole is a novel kind triazole drug of anti-fungal infection which was first successfully developed by the American Pfizer with broad-spectrum anti-fungal effect. It belongs to a kind of systemic anti-fungal products and has high selectivity on the inhibitory effect of the fungal cytochrome P450-dependent enzyme. It is also a kind of potent and specific inhibitor for the fungi alcohol synthesis. Clinically it is mainly used for the treatment of vaginal candidiasis, thrush, atrophic oral candidiasis, fungal meningitis, pulmonary fungal infections, abdominal infections, urinary tract infections and skin fungi infection. The main indication for fluconazole as follows: 1, systemic candidiasis: including candidemia, disseminated candidiasis and other forms of invasive Candida infections such as the peritoneum, endocardium, lungs and urinary tract infections. It can also be applied to patients of malignant tumors, special-care patients, patients who received radiotherapy, chemotherapy or immunosuppressive therapy as well as patients who are susceptible to other factors such as infection of Candida. It can also be used for prevention of the occurrence of candida infection for bone marrow transplant patients upon receiving cytotoxic drugs treatment or radiation treatment.

    Fluconazole chemical structure

    Fluconazole - an overview ScienceDirect Topics -, RFHAOTPXVQNOHP-CQOLUAMGSA-N C13H12F2N6O - PubChem

  2. Can i legally order viagra online
  3. Buy retin a janssen
  4. Can you buy diflucan otc
  5. Lasix with potassium
  6. Sertraline ingredients
  7. Fluconazole ≥98% HPLC, powder; CAS Number 86386-73-4; Synonym 2-2,4-Difluorophenyl-1. Linear Formula C13H12F2N6O; find Sigma-Aldrich-F8929 MSDS, related peer-reviewed papers. plasmid vector for molecular cloning.

    • Fluconazole ≥98% HPLC, powder Sigma-Aldrich.
    • KEGG DRUG Fluconazole.
    • Fluconazole Structure - C13H12F2N6O Mol-Instincts.

    Compound Type. Amine; Antifungal Agent; Drug; Metabolite; Organic Compound; Organofluoride; Synthetic Compound. Chemical Structure. Learn about Diflucan Fluconazole may treat, uses, dosage, side effects, drug. with an empirical formula of C13H12F2N6O and molecular weight of 306.3. The structural formula is DIFLUCAN® Fluconazole - Structural Formula Illustration. Melting point °C, 138-140 °C, 3248 water solubility, slightly soluble in water.

     
  8. wable User

    For many the problem of erectile dysfunction (ED)is a temporary blip in an otherwise fulfilling sex life, but for some it can be more long term, resulting in distress and even depression. Looking on the bright side, there are some very effective remedies out there. So let’s get to grips with the question of Viagra versus other alternatives. Viagra is a licensed pharmaceutical medicine used to treat ED and impotence. Its active ingredient is sildenafil, supplied in doses ranging from 25mg to 100 mg per tablet. There are other licensed drugs available, and like Viagra, they are known as phosphodiesterase type 5 inhibitors (PDE-5). The brand names of these products are Cialis (tadalafil)and Levitra (vardenafil), and Spedra (avanafil). Better than Viagra List of the Best Viagra Alternative that Works. Viagra Online # Generic Viagra Sites Like Backpage – Top Best Alternatives
     
  9. Alise Guest

    Beta-blockers Dampening The Body's Ability To Burn Fat - Women. Beta blockers, such as atenolol and propranolol, reduce the body's ability. G. Sheps, hypertension specialist “The average weight gain is no.

    Update on weight gain because of propranolol and lack of energy.